NSAIDs and Anti Inflamatories

Anti-histamines

Livostin , Otrivine-antistin

Alomide , Hay Crom , Optichrom , Rapitil , Vividrin

Acular , Ocufen , Voltarol

Acular®

ketotolac trometamol 0.5%
Preservatives:- benzalkonium chloride, EDTA
Category :- POM
Availability:- ACULAR gtt.
Current optometric application/s (UK):- none.
Indications for use:- management of ocular inflammation associated with surgical procedures inside the eye, e.g. cataract operations.
Contraindication/s:- known allergy (sensitivity), avoid use in patients with known sensitivity to other NSAID's (including ASA); not for use in pregnancy and lactation.
Special precaution/s:- safety and efficacy in children has not been established; consider potential for interactions with systemic heparin or warfarin (anti-coagulant therapies).
Adverse drug reaction/s:- transient ocular irritation. Comment's: - NEW PHARMACEUTICAL - any adverse reaction should be reported to CSM.
Comment/s:-

Alomide®

lodoxamide tromethamine 0.1 %
Preservatives:- benzalkonium chloride, EDTA.
Category :- POM
Availability:- ALOMIDE gtt.
Current optometric application's (UK):- none.
Indications for use:- management of allergic conjunctivitis
Contraindication's :- known allergy (sensitivity)
Special precautions:- limit use in pregnancy and lactation; safety and efficacy in children below the age of 4 years has not been established.
Adverse drug reaction/s:- transient ocular irritation.
Comment's: - patient's should be advised that the efficacy of ALOMIDE therapy requires regular dosing, as indicated.

Hay Crom®

sodium cromoglycate 2%
Preservatives:- benzalkonium chloride, disodium edetate.
Category :- POM
Availability:- HAY CROM gtt.
Current optometric application/s (UK):- none.
Contraindication/s:- soft contact lenses.
Drug interaction/s:-
Special precaution/s:-
Adverse drug reaction/s:- burning or stinging on instillation.
Comment's: -Comment/s:- patient's should be advised that the efficacy of Hay Crom®: therapy requires regular dosing, as indicated.

Livostin^TM

levocabastine hydrochloride 0.05%
Preservatives:- benzalkonium chloride, EDTA.
Category :- POM
Availability:- LIVOSTIN gtt.
Current optometric application/s (UK):- none
Contraindication/s:- known allergy (sensitivity), known kidney dysfunction (renal impairment).
Drug interaction/s:-
Special precaution/s:- safety and efficacy in children has not been established, not recommended for children under age of 9 years; limit use in pregnancy and lactation; consider severity of any concurrent bronchial disease and need for other medications.
Adverse drug reaction/s:- transient ocular irritation.
Comment/s:- NEW PHARMACEUTICAL - any adverse reaction should be reported to CSM.Topical histamine H1 receptor antagonist.

Livostin^TM Direct Eydrops

Active ingredient/s:- levocabastine 0.05 %
Preservatiues:- benzalkonium chloride, EDTA.
Indications for use:- seasonal conjunctivitis
Category:- P
Availability:- LIVOSTIN DIRECT 0.05 % gtt, 3 mL bottle
Current optometric application/s (UK):- shorter and medium term management of seasonal allergic conjunctivitis
Contraindication/s:- known allergy (sensitivity) to the drug or any other ingedients of the pharmaceutical; major kidney disease; not to be used in pregnancy
Special precautions/s:- limit total period of use to 4 weeks in any year; safety and efficay for use in children below the age of 12 years has not been established (not recommended)
Adverse drug reaction/s:-
Comments:-

Ocufen®

flurbiprofen sodium 0.03%
Preservatives:- none.
Category :- POM
Availability:- OCUFEN gtt, single dose units.
Current optometric application/s (UK):- none.
Contraindication/s:-
Drug interaction/s:-
Special precaution/s:-
Adverse drug reaction/s:-
Comment/s:-

Optichrom®

Sodium cromoglycate 2%
Preservatives:-
Category:- P
Availability:- OPTICHROM gtt.
Current optometric application/s (UK):- none
Contraindication/s:-
Special precaution/s:- not with soft contact lenses.
Adverse drug reaction/s:-
Comment's: -Comment/s:- patient's should be advised that the efficacy of Opticrom®: therapy requires regular dosing, as indicated.

Otrivine-antistin®

xylometazoline 0.05%, antazoline 0.5%.
Preservatives:-
Category:- P
Current optometric application/s (UK):- relief of redness and itching due to allergies.
Contraindication/s:- not for narrow angle glaucoma or contact lens patients.
Special precaution/s:- care with hypertension, hyperthyroidism, diabetes, coronary disease and dry eye patients.
Adverse drug reaction/s:- rebound congestion, stinging, headache, drowsiness, and blurred vision.
Comment/s:-

Rapitil®

nedocromil sodium 2%
Preservatives:- benzethonium chloride.
Category :- POM
Availability:- RAPITIL gtt.
Current optometric application/s (UK):- none.
Contraindication/s:- not with soft contact lenses.
Drug interaction/s:-
Special precaution/s:- not during pregnancy.
Adverse drug reaction/s:- irritation on instillation and adverse taste.
Comment/s:-

Vividrin®

sodium cromoglycate 2%
Preservatives:- benzalkonium chloride, EDTA
Category :- POM
Availability:- VIVIDRIN gtt.
Current optometric application/s (UK):- none.
Contraindication/s:- not with soft contact lenses.
Drug interaction/s:-
Special precaution/s:- not during pregnancy.
Adverse drug reaction/s:- irritation on instillation.
Comment/s:-

Voltarol®

diclofenac sodium 0.1%
Preservatives:-
Category :- POM
Availability:- VOLTAROL gtt. single dose units.
Current optometric application/s (UK):- none.
Contraindication/s:-
Drug interaction/s:-
Special precaution/s:-
Adverse drug reaction/s:-
Comment/s:- not at present recommended for use in non-infective conjunctivitis. recommended use only as a pre and post operative drug in cataract surgery.